Zollinger–Ellison syndrome, n.

zollinger-ellison-syndrome
http://www.oed.com/dictionary/zollinger-ellison-syndrome_n%3Ftab%3Dmeaning_and_use
First published 1986; not fully revised

# Zollinger–Ellison syndromenoun

## Earlier version

- Zollinger–Ellison syndrome in OED Second Edition (1989)

## Factsheet

### What does the noun Zollinger–Ellison syndrome mean?

There is one meaning in OED's entry for the noun Zollinger–Ellison syndrome. See ‘Meaning & use’ for definition, usage, and quotation evidence.

#### Entry status

OED is undergoing a continuous programme of revision to modernize and improve definitions. This entry has not yet been fully revised.

### How is the noun Zollinger–Ellison syndrome pronounced?

#### British English

/ˌzɒlᵻndʒə(r)ˈɛlᵻs(ə)n ˌsɪndrəʊm/
zol-uhn-juhr-EL-uh-suhn sin-drohm

#### U.S. English

/ˌzɑləndʒərˈɛləsən ˌsɪnˌdroʊm/
zah-luhn-juhr-EL-uh-suhn sin-drohm
/ˌzɑlɪŋɡərˈɛləsən ˌsɪnˌdroʊm/
zah-ling-guhr-EL-uh-suhn sin-drohm

### Where does the noun Zollinger–Ellison syndrome come from?

Earliest known use

1950s

The earliest known use of the noun Zollinger–Ellison syndrome is in the 1950s.

OED's earliest evidence for Zollinger–Ellison syndrome is from 1956, in a text by Eiseman and Maynard.

From proper names, combined with an English element.

Etymons: proper names Zollinger, Ellison, syndrome n.

### Nearby entries

1. zoism, n. 1900–
2. zoist, n. 1843–
3. zoistic, adj. 1849–
4. zoite, n. 1963–
5. -zoite, comb. form
6. zol, n. 1946–
7. Zolaesque, adj. 1886–
8. Zolaism, n. 1882–
9. Zolaist, n. 1886–
10. Zolaize, v. 1886–
11. Zollinger–Ellison syndrome, n.1956–
12. Zöllner, n. 1890–
13. zollverein, n. 1843–
14. zolotnik, n. 1783–
15. zombie, n. 1788–
16. zombie apocalypse, n. 1982–
17. zombied, adj. 1972–
18. zombie-esque, adj. 1946–
19. zombie-like, adj. & adv. 1932–
20. zombie worm, n. 2005–
21. zombification, n. 1968–

## Etymology

### Summary

From proper names, combined with an English element.
Etymons: proper names Zollinger, Ellison, syndrome n.
< the name of Robert M. Zollinger (1903–92) and E. H. Ellison (1918–70), American physicians, who described the syndrome in 1955 (Ann. Surg. CXLII. 709) + syndrome n.

## Meaning & use

Pathology.

1. 1956–
   A syndrome characterized by excessive gastric acid secretion (producing recurrent peptic ulcers) associated with a gastrin-secreting tumour or hyperplasia of the islet cells of the pancreas.
   1. 1956

      > For the sake of simplicity we propose this clinical entity be called the Zollinger-Ellison syndrome.

      Eiseman & Maynard in Gastroenterology vol. XXXI. 302
   2. 1960

      > Since that time [sc. 1955] over 100 instances of co-existent peptic ulcer and islet cell tumours have been described and the association appears to constitute a clinical entity called, by general consent, the ‘Zollinger-Ellison syndrome’.

      Journal Royal Coll. of Surgeons of Edinburgh vol. 5 191
   3. 1962

      > The characteristics of the Zollinger–Ellison syndrome are extreme gastric hyper~secretion, intractable peptic ulceration..and either hyperplasia or tumour of the islet-cells of the pancreas.

      Lancet 12 May 1003/2
   4. 1974

      > In the Zollinger-Ellison syndrome, ulcers may occur at the duodenojejunal junction.

      R. M. Kirk et al., Surgery vi. 85/1
   pathology
   1. pancreatitis 1842–
      Inflammation of the pancreas.
   2. Zollinger–Ellison syndrome 1956–
      A syndrome characterized by excessive gastric acid secretion (producing recurrent peptic ulcers) associated with a gastrin-secreting tumour or…
   View in Historical Thesaurus

## Pronunciation

### British English

/ˌzɒlᵻndʒə(r)ˈɛlᵻs(ə)n ˌsɪndrəʊm/
zol-uhn-juhr-EL-uh-suhn sin-drohm

### U.S. English

/ˌzɑləndʒərˈɛləsən ˌsɪnˌdroʊm/
zah-luhn-juhr-EL-uh-suhn sin-drohm
/ˌzɑlɪŋɡərˈɛləsən ˌsɪnˌdroʊm/
zah-ling-guhr-EL-uh-suhn sin-drohm
/ˌzɑləndʒərˈɛləsən ˌsɪndrəm/
zah-luhn-juhr-EL-uh-suhn sin-druhm
/ˌzɑlɪŋɡərˈɛləsən ˌsɪndrəm/
zah-ling-guhr-EL-uh-suhn sin-druhm

####

##### Consonants

- ppea
- ttea
- kkey
- bbuy
- ddye
- ɡguy
- tʃchore
- dʒjay
- ffore
- θthaw
- ssore
- ʃshore
- vvee
- ðthee
- zzee
- ʒbeige
- xloch
- hhay
- llay
- ɬrhingyll
- rray
- wway
- jyore
- mmay
- nnay
- ŋsing

Some consonants can take the function of the vowel in unstressed syllables. Where necessary, a syllabic marker diacritic is used, hence /ˈpɛtl/ but /ˈpɛtl̩i/.

##### Vowels

- iːfleece
- ihappy
- ɪkit
- ɛdress
- atrap, bath
- ɑːstart, palm, bath
- ɒlot
- ɔːthought, force
- ʌstrut
- ʊfoot
- uːgoose
- əletter
- əːnurse
- ɪənear
- ɛːsquare
- ʊəcure
- eɪface
- ʌɪpride
- aʊmouth
- əʊgoat
- ɔɪvoice
- ãgratin
- ɒ̃salon
- ᵻ(/ɪ/-/ə/)
- ᵿ(/ʊ/-/ə/)

##### Other symbols

- The symbol ˈ at the beginning of a syllable indicates that that syllable is pronounced with primary stress.
- The symbol ˌ at the beginning of a syllable indicates that that syllable is pronounced with secondary stress.
- Round brackets ( ) in a transcription indicate that the symbol within the brackets is optional.

View the pronunciation model here.

####

##### Consonants

- ppea
- ttea
- kkey
- bbuy
- ddye*
- ɡguy
- tʃchore
- dʒjay
- ffore
- θthaw
- ssore
- ʃshore
- vvee
- ðthee
- zzee
- ʒbeige
- xloch
- hhay
- llay
- rray
- wway
- jyore
- mmay
- nnay
- ŋsing

* /d/ also represents a 'tapped' /t/ as in

Some consonants can take the function of the vowel in unstressed syllables. Where necessary, a syllabic marker diacritic is used, hence /ˈpɛd(ə)l/ but /ˈpɛdl̩i/.

##### Vowels

- ifleece, happy
- ɪkit
- ɛdress
- ætrap, bath
- ɑlot, palm, cloth, thought
- ɑrstart
- ɔcloth, thought
- ɔrnorth, force
- ʊfoot
- ugoose
- əstrut, comma
- ərnurse, letter
- ɪ(ə)rnear
- ɛ(ə)rsquare
- ʊ(ə)rcure
- eɪface
- aɪpride
- aʊmouth
- oʊgoat
- ɔɪvoice
- ɑ̃gratin
- æ̃salon
- ᵻ(/ɪ/-/ə/)
- ᵿ(/ʊ/-/ə/)

##### Other symbols

- The symbol ˈ at the beginning of a syllable indicates that that syllable is pronounced with primary stress.
- The symbol ˌ at the beginning of a syllable indicates that that syllable is pronounced with secondary stress.
- Round brackets ( ) in a transcription indicate that the symbol within the brackets is optional.

View the pronunciation model here.

####

Simple text respell breaks words into syllables, separated by a hyphen. The syllable which carries the primary stress is written in capital letters. This key covers both British and U.S. English Simple Text Respell.

##### Consonants

b, d, f, h, k, l, m, n, p, r, s, t, v, w and z have their standard English values

- gguy
- jjay
- yyore
- chchore
- khloch
- shshore
- ththaw
- dhthee
- zhbeige

##### Vowels

- atrap
- ahpalm
- airsquare
- arstart
- arrcarry (British only)
- awthought
- ayface
- a(ng)gratin
- edress
- eefleece
- eerdeer
- errmerry
- ikit
- ighpride
- irrmirror
- olot (British only)
- ohgoat
- oogoose
- oorcure
- orforce
- orrsorry (British only)
- owmouth
- oyvoice
- o(ng)salon
- ustrut
- uhletter
- urnurse
- urrhurry
- uufoot

Zollinger–Ellison syndrome, n. was first published in 1986; not fully revised.

Zollinger–Ellison syndrome, n. was last modified in July 2023.