< the name of Robert M. Zollinger (1903–92) and E. H. Ellison (1918–70), American physicians, who described the syndrome in 1955 (Ann. Surg. CXLII. 709) + syndromen.
Meaning & use
Pathology.
1956–
A syndrome characterized by excessive gastric acid secretion (producing recurrent peptic ulcers) associated with a gastrin-secreting tumour or hyperplasia of the islet cells of the pancreas.
1956
For the sake of simplicity we propose this clinical entity be called the Zollinger-Ellison syndrome.
Eiseman & Maynard in Gastroenterologyvol. XXXI. 302
1960
Since that time [sc. 1955] over 100 instances of co-existent peptic ulcer and islet cell tumours have been described and the association appears to constitute a clinical entity called, by general consent, the ‘Zollinger-Ellison syndrome’.
Journal Royal Coll. of Surgeons of Edinburghvol. 5 191
1962
The characteristics of the Zollinger–Ellison syndrome are extreme gastric hyper~secretion, intractable peptic ulceration..and either hyperplasia or tumour of the islet-cells of the pancreas.
Lancet 12 May 1003/2
1974
In the Zollinger-Ellison syndrome, ulcers may occur at the duodenojejunal junction.
Some consonants can take the function of the vowel in unstressed syllables. Where necessary, a syllabic marker diacritic is used, hence /ˈpɛtl/ but /ˈpɛtl̩i/.
Vowels
iːfleece
ihappy
ɪkit
ɛdress
atrap, bath
ɑːstart, palm, bath
ɒlot
ɔːthought, force
ʌstrut
ʊfoot
uːgoose
əletter
əːnurse
ɪənear
ɛːsquare
ʊəcure
eɪface
ʌɪpride
aʊmouth
əʊgoat
ɔɪvoice
ãgratin
ɒ̃salon
ᵻ(/ɪ/-/ə/)
ᵿ(/ʊ/-/ə/)
Other symbols
The symbol ˈ at the beginning of a syllable indicates that that syllable is pronounced with primary stress.
The symbol ˌ at the beginning of a syllable indicates that that syllable is pronounced with secondary stress.
Round brackets ( ) in a transcription indicate that the symbol within the brackets is optional.
Some consonants can take the function of the vowel in unstressed syllables. Where necessary, a syllabic marker diacritic is used, hence /ˈpɛd(ə)l/ but /ˈpɛdl̩i/.
Vowels
ifleece, happy
ɪkit
ɛdress
ætrap, bath
ɑlot, palm, cloth, thought
ɑrstart
ɔcloth, thought
ɔrnorth, force
ʊfoot
ugoose
əstrut, comma
ərnurse, letter
ɪ(ə)rnear
ɛ(ə)rsquare
ʊ(ə)rcure
eɪface
aɪpride
aʊmouth
oʊgoat
ɔɪvoice
ɑ̃gratin
æ̃salon
ᵻ(/ɪ/-/ə/)
ᵿ(/ʊ/-/ə/)
Other symbols
The symbol ˈ at the beginning of a syllable indicates that that syllable is pronounced with primary stress.
The symbol ˌ at the beginning of a syllable indicates that that syllable is pronounced with secondary stress.
Round brackets ( ) in a transcription indicate that the symbol within the brackets is optional.
Simple text respell breaks words into syllables, separated by a hyphen. The syllable which carries the primary stress is written in capital letters. This key covers both British and U.S. English Simple Text Respell.
Consonants
b, d, f, h, k, l, m, n, p, r, s, t, v, w and z have their standard English values
gguy
jjay
yyore
chchore
khloch
shshore
ththaw
dhthee
zhbeige
Vowels
atrap
ahpalm
airsquare
arstart
arrcarry (British only)
awthought
ayface
a(ng)gratin
edress
eefleece
eerdeer
errmerry
ikit
ighpride
irrmirror
olot (British only)
ohgoat
oogoose
oorcure
orforce
orrsorry (British only)
owmouth
oyvoice
o(ng)salon
ustrut
uhletter
urnurse
urrhurry
uufoot
Zollinger–Ellison syndrome, n. was first published in 1986; not fully revised.
Zollinger–Ellison syndrome, n. was last modified in July 2023.